From Joshua trees and the Grand Canyon to roadside burger joints and the cosmopolitan streets of San Francisco, this region is loaded with the intriguing and the incredible. Best of all, this Los Angeles to San Francisco itinerary is structured so that those short on time can experience the region's best. At any of the sights you’ll get great pictures and a greater appreciation of what you’re seeing. Best of all, national park entrances are included, so you can explore Yosemite and still try your luck in Las Vegas.