Landlocked Bolivia is a quintessential South American country both in terms of the immensity of its landscapes and its strong indigenous culture. Although little-known, Amboró National Park boasts almost unparalleled bio-diversity and the charming, albeit rustic, gateway town of Samaipata also gives access to the nearby Pre-Columbian UNESCO site of El Fuerte. Nowhere else on Earth can you find salt flats of comparable scale to Salar de Uyuni; a comprehensive three-day 4WD adventure reveals its multi-coloured lagoons, cacti islands and spouting geysers. In stark contrast to these natural wonders are the vibrant cities of Sucre, Potosi and La Paz whose heritage was shaped by both the Incas and the Spanish Conquistadores. Finally, wind down with a night in an eco-lodge on the Isla del Sol overlooking the deep, tranquil waters of Lake Titicaca - fringed by snow-capped peaks of the Cordillera Real.